New Technologies & Large Animal Models in Biomedical Research


FMRI of pigExploring new models

Large animal models offer new opportunities to explore important questions in biomedical and dual-purpose research. This symposium will provide a venue to learn about successful research programs that use large animal models, explore ideas and develop collaborations with fellow researchers interested in incorporating these models into their research programs.

Monday, March 27, 2017
8:00 a.m. to 6:00 p.m.

Heritage Room
University Club of Michigan State University
3535 Forest Road, Lansing, MI 48910

Map and parking information.




Symposium organized by Dr. Keith Latham, Dr. Asgerally Fazleabas and Dr. Almudena Veiga-Lopez on behalf of the Reproductive and Developmental Science Program



8-8:30 Introductory lecture: 
Perspectives of an old cow wonk: Lessons learned from past workshops and the bovine as a dual purpose model in agriculture and biomedicine, James Ireland (Michigan State University)

8:30-8:45 Discussion
Keith Latham (Michigan State University)

8:45-10:00 Session 1: Asthma and Respiratory Disease

  • 8:45-8:50 Introduction Keith English (Michigan State University), moderator
  • 8:50-9:25 Robert Bartlett, MD & Alvaro Rojas-Pena, MD (University of Michigan), Animals in artificial organ research
  • 9:25-10:00 Jack Harkema (Michigan State University), Animals models of air pollutant-Induced asthma and rhinitis: What we have learned from monkeys, rats and mice

10:00-10:15 Coffee Break

10:15- 11:25 Session 2: Musculoskeletal Disease in Large Animal Models
Kurt Hankenson (MSU), moderator

  • 10:15-10:50 Kurt Hankenson (MSU),  Large animal models of bone regeneration
  • 10:50-11:25 Lisa Larkin (University of Michigan), Using sheep as a large animal model to test ligament/tendon repairs

11:25-12:30 Catered light lunch

12:30-2:20 Session 3: Environmental Factors Affecting Adult and Fetal Health
Almudena Veiga-Lopez (Michigan State University), moderator

  • 12:30-12:35 Introduction Almudena Veiga-Lopez (Michigan State University)
  • 12:35-1:10 Adam Moeser (Michigan State University), Porcine models of stress-induced gastrointestinal disorders: pathophysiology and translational implications
  • 1:10-1:45 Stephen Ford (University of Wyoming), The development of a sheep model to study the multigenerational impact of maternal overnutrition/obesity in altering offspring phenotype
  • 1:45-2:20 RD Roghair (University of Iowa), Translational cardiovascular investigations in sheep and transgenic pigs

2:20-2:30 Coffee Break

2:30-5:00 Session 4: New Technologies
Ariela Shikanov (University of Michigan), moderator

  • 2:45-3:15 Introduction Ariela Shikanov (University of Michigan), Engineering the follicle environment
  • 3:15-3:50 Lonnie Shea, (University of Michigan), Local and systemic immunomodulation for regenerative medicine
  • 3:50-4:25 Randy Prather (University of Missouri), Genome editing-state of the art, promises, pitfalls & applications
  • 4:25-5:00 Tom Spencer (University of Missouri), Understanding Fertility in Agriculturally Important Large Animals: Impacts of Technology

5:00-6:00 Reception

Please contact Kailey Vincent at (517) 432-4449 or email with any questions.